Course Details

• Credit: 3
• Semester: 1
• Prerequisite: IBG213/4 Bioreactor Operation (sequential)

Synopsis

This course covers introduction to fermentation process, different operation modes, design of experiment and optimisation process. Kinetics and modelling of fermentation; kinetic models, simulation tools. Basic mass balance; mass balance as inspection data, process in a balanced condition. Estimation of kinetic parameter values; measurement of growth, rates of substrate consumption, rates of product formation, environmental factors affecting growth rate. Model of batch fermentation; simulation of growth in the batch fermentation and measurement of simulation parameters. Model of continuous fermentation; simulation of growth in the continuous fermentation and measurement of simulation parameters. Model of fed-batch fermentation; simulation of growth in the fed-batch fermentation and measurement of simulation parameters.